MALFORMACIÓN CAVERNOSA DEL TRONCO ENCEFÁLICO CON RESOLUCIÓN QUIRÚRGICA EN EL HOSPITAL DE ESPECIALIDADES EUGENIO ESPEJO
Palabras clave:
Malformación cavernosa, microcirugía, escala de Rankin
Resumen
Las malformaciones cavernosas son parte de la gran variedad de patologias vasculares cerebrales, lo más común es que su presentación sea en áreas supratentoriales del cerebro y en pocos casos se presenta en áreas infratentoriales para los cuales el tratamiento de elección es la microcirugía, con resultados beneficiosos para el paciente y mejora de la clínica del mismo. Su resultado siempre dependerá mucho de la técnica quirúrgica y la experticia del neurocirujano.
A continuación, se reporta un caso clínico de un adulto joven con diagnóstico de malformación cavernosa con evolución clínica durante 10 meses que fue intervenido quirúrgicamente en el Hospital de Especialidades Eugenio Espejo en el servicio de neurocirugía.
Citas
Flemming KD, Lanzino G. Cerebral Cavernous Malformation: What a Practicing Clinician Should Know. Mayo Clin Proc. 2020 Sep;95(9):2005–20.
2. Li Z, Ma L, Quan K, Liu P, Shi Y, Liu Y, et al. Rehemorrhage of brainstem cavernous malformations: a benchmark approach to individualized risk and severity assessment. J Neurosurg. 2023 Jul 1;139(1):94–105.
3. Velz J, Neidert MC, Yang Y, Akeret K, Nakaji P, Regli L, et al. Mortality in Patients with Brainstem Cavernous Malformations. Cerebrovasc Dis Basel Switz. 2021;50(5):574–80.
4. Albalkhi I, Shafqat A, Bin-Alamer O, Mallela AN, Kuminkoski C, Labib MA, et al. Long-term functional outcomes and complications of microsurgical resection of brainstem cavernous malformations: a systematic review and meta-analysis. Neurosurg Rev. 2023 Sep 20;46(1):252.
5. Flemming KD, Smith E, Marchuk D, Derry WB. Familial Cerebral Cavernous Malformations. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJ, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993 [cited 2023 Nov 28]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK1293/
6. Horne MA, Flemming KD, Su IC, Stapf C, Jeon JP, Li D, et al. Clinical course of untreated cerebral cavernous malformations: a meta-analysis of individual patient data. Lancet Neurol. 2016 Feb;15(2):166–73.
7. Li D, Zheng JJ, Weng JC, Liu PP, Wu ZY, Zhang LW, et al. Neurological outcomes of untreated brainstem cavernous malformations in a prospective observational cohort and literature review. Stroke Vasc Neurol. 2021 Dec;6(4):501–10.
8. Akers A, Al-Shahi Salman R, A Awad I, Dahlem K, Flemming K, Hart B, et al. Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel. Neurosurgery. 2017 May 1;80(5):665–80.
9. Xie MG, Li D, Guo FZ, Zhang LW, Zhang JT, Wu Z, et al. Brainstem Cavernous Malformations: Surgical Indications Based on Natural History and Surgical Outcomes. World Neurosurg. 2018 Feb;110:55–63.
10. Rinkel LA, Al-Shahi Salman R, Rinkel GJ, Greving JP. Radiosurgical, neurosurgical, or no intervention for cerebral cavernous malformations: A decision analysis. Int J Stroke Off J Int Stroke Soc. 2019 Dec;14(9):939–45.
11. Yang Z, Yu G, Zhu W, Chen L, Song J, Mao Y. The benefit and outcome prediction of acute surgery for hemorrhagic brainstem cavernous malformation with impending respiratory failure. J Clin Neurosci Off J Neurosurg Soc Australas. 2021 Nov;93:213–20.
12. Walcott BP, Choudhri O, Lawton MT. Brainstem cavernous malformations: Natural history versus surgical management. J Clin Neurosci Off J Neurosurg Soc Australas. 2016 Oct;32:164–5.
13. Kikuta KI, Isozaki M, Higashino Y, Kodera T, Arishima H, Matsuda K, et al. Functional Outcomes of Microsurgical Resection for Cavernous Malformations of the Brainstem. Adv Tech Stand Neurosurg. 2022;44:121–32.
14. Nagy G, Burkitt W, Stokes SS, Bhattacharyya D, Yianni J, Rowe JG, et al. Contemporary radiosurgery of cerebral cavernous malformations: Part 1. Treatment outcome for critically located hemorrhagic lesions. J Neurosurg. 2018 Jul 27;1–9.
15. Nagy G, Stokes SS, Erőss LG, Bhattacharyya D, Yianni J, Rowe JG, et al. Contemporary radiosurgery of cerebral cavernous malformations: Part 2. Treatment outcome for hemispheric lesions. J Neurosurg. 2018 Jul 1;1–9.
16. Aboukais R, Estrade L, Devos P, Blond S, Lejeune JP, Reyns N. Gamma Knife Radiosurgery of Brainstem Cavernous Malformations. Stereotact Funct Neurosurg. 2016;94(6):397–403.
17. Kim BS, Kim KH, Lee MH, Lee JI. Stereotactic Radiosurgery for Brainstem Cavernous Malformations: An Updated Systematic Review and Meta-Analysis. World Neurosurg. 2019 Oct;130:e648–59.
2. Li Z, Ma L, Quan K, Liu P, Shi Y, Liu Y, et al. Rehemorrhage of brainstem cavernous malformations: a benchmark approach to individualized risk and severity assessment. J Neurosurg. 2023 Jul 1;139(1):94–105.
3. Velz J, Neidert MC, Yang Y, Akeret K, Nakaji P, Regli L, et al. Mortality in Patients with Brainstem Cavernous Malformations. Cerebrovasc Dis Basel Switz. 2021;50(5):574–80.
4. Albalkhi I, Shafqat A, Bin-Alamer O, Mallela AN, Kuminkoski C, Labib MA, et al. Long-term functional outcomes and complications of microsurgical resection of brainstem cavernous malformations: a systematic review and meta-analysis. Neurosurg Rev. 2023 Sep 20;46(1):252.
5. Flemming KD, Smith E, Marchuk D, Derry WB. Familial Cerebral Cavernous Malformations. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJ, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993 [cited 2023 Nov 28]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK1293/
6. Horne MA, Flemming KD, Su IC, Stapf C, Jeon JP, Li D, et al. Clinical course of untreated cerebral cavernous malformations: a meta-analysis of individual patient data. Lancet Neurol. 2016 Feb;15(2):166–73.
7. Li D, Zheng JJ, Weng JC, Liu PP, Wu ZY, Zhang LW, et al. Neurological outcomes of untreated brainstem cavernous malformations in a prospective observational cohort and literature review. Stroke Vasc Neurol. 2021 Dec;6(4):501–10.
8. Akers A, Al-Shahi Salman R, A Awad I, Dahlem K, Flemming K, Hart B, et al. Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel. Neurosurgery. 2017 May 1;80(5):665–80.
9. Xie MG, Li D, Guo FZ, Zhang LW, Zhang JT, Wu Z, et al. Brainstem Cavernous Malformations: Surgical Indications Based on Natural History and Surgical Outcomes. World Neurosurg. 2018 Feb;110:55–63.
10. Rinkel LA, Al-Shahi Salman R, Rinkel GJ, Greving JP. Radiosurgical, neurosurgical, or no intervention for cerebral cavernous malformations: A decision analysis. Int J Stroke Off J Int Stroke Soc. 2019 Dec;14(9):939–45.
11. Yang Z, Yu G, Zhu W, Chen L, Song J, Mao Y. The benefit and outcome prediction of acute surgery for hemorrhagic brainstem cavernous malformation with impending respiratory failure. J Clin Neurosci Off J Neurosurg Soc Australas. 2021 Nov;93:213–20.
12. Walcott BP, Choudhri O, Lawton MT. Brainstem cavernous malformations: Natural history versus surgical management. J Clin Neurosci Off J Neurosurg Soc Australas. 2016 Oct;32:164–5.
13. Kikuta KI, Isozaki M, Higashino Y, Kodera T, Arishima H, Matsuda K, et al. Functional Outcomes of Microsurgical Resection for Cavernous Malformations of the Brainstem. Adv Tech Stand Neurosurg. 2022;44:121–32.
14. Nagy G, Burkitt W, Stokes SS, Bhattacharyya D, Yianni J, Rowe JG, et al. Contemporary radiosurgery of cerebral cavernous malformations: Part 1. Treatment outcome for critically located hemorrhagic lesions. J Neurosurg. 2018 Jul 27;1–9.
15. Nagy G, Stokes SS, Erőss LG, Bhattacharyya D, Yianni J, Rowe JG, et al. Contemporary radiosurgery of cerebral cavernous malformations: Part 2. Treatment outcome for hemispheric lesions. J Neurosurg. 2018 Jul 1;1–9.
16. Aboukais R, Estrade L, Devos P, Blond S, Lejeune JP, Reyns N. Gamma Knife Radiosurgery of Brainstem Cavernous Malformations. Stereotact Funct Neurosurg. 2016;94(6):397–403.
17. Kim BS, Kim KH, Lee MH, Lee JI. Stereotactic Radiosurgery for Brainstem Cavernous Malformations: An Updated Systematic Review and Meta-Analysis. World Neurosurg. 2019 Oct;130:e648–59.
Publicado
2024-08-01
Cómo citar
Alvarado, R., Fernández, O., & Chasipanta, J. (2024). MALFORMACIÓN CAVERNOSA DEL TRONCO ENCEFÁLICO CON RESOLUCIÓN QUIRÚRGICA EN EL HOSPITAL DE ESPECIALIDADES EUGENIO ESPEJO. REFLEXIONES. Revista científica Del Hospital Eugenio Espejo, 21(2). https://doi.org/10.16921/reflexiones.v21i2.115
Sección
Reportes de casos
Derechos de autor 2024 REFLEXIONES. Revista científica del Hospital Eugenio Espejo
Esta obra está bajo licencia internacional Creative Commons Reconocimiento 4.0.
