Coinfection of histoplasmosis and disseminated tuberculosis in a patient without HIV
Abstract
Disseminated histoplasmosis and systemic tuberculosis are opportunistic infections that have traditionally been associated with people with severe immunosuppression, being demonstrated above all in patients with HIV who are in the AIDS phase. The medical literature with few reports on said coinfection in patients without HIV was reviewed. The case of an average adult with a history of smoking and occasional cocaine use is presented, who was admitted due to a progressively growing ulcer on the tongue with histopathological report of histoplasmosis, in addition to presenting respiratory symptoms and constitutional syndrome for which sputum smear microscopies were taken. and urine, which were positive, diagnosing coinfection of histoplasmosis and disseminated tuberculosis, in a patient with negative serology. Antifungal treatment and amphotericin B deoxycholate were administered together for subsequent maintenance with itraconazole with good clinical and laboratory response.
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